Out-licensing

Rabbit polyclonal antibodies that recognize the human and mouse S100A15 proteins

This technology describes rabbit polyclonal antibodies that recognize the human and mouse S100A15 proteins. S100A15 is involved in epidermal differentiation and inflammation, and is dysregulated in skin tumors and inflammatory psoriasis.

Applications:

• Diagnostic tool for evaluation of agents that alter skin pathology
• Research tool to probe the role of S100A15 during epidermal maturation, skin carcinogenesis, and inflammation
• Diagnostic tool for the clinical evaluation of skin tumors and inflammatory diseases such as psoriasis

Publication:
R Wolf et al., "The mouse S100A15 ortholog parallels genomic organization, structure, gene expression, and protein-processing pattern of the human S100A7/A15 subfamily during epidermal maturation," J Invest Dermatol. 2006 Jul;126(7):1600-1608.  [PubMed abs]

Early Stage

HHS Reference No. E-145-2006/0 -- Research Tool

Inventors:
Ronald Wolf, Stuart H. Yuspa, Paul Goldsmith, and Christopher J. Voscopoulos (NCI)

Licensees Sought:
Available for non-exclusive licensing under a Biological Materials License.