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Bone Morphogenetic Variants, Compositions and Methods of Treatment
Nucleic acids encoding human Cartilage-Derived Morphogenetic Protein-1 (hCDMP-1) variant polypeptides
Full description
The invention identifies proteins belonging to TGF-Beta
superfamily that promote repair of menisci, cruciate and
collateral ligaments of the knee, and rotator cuff tendons. The
application claims nucleic acids encoding human Cartilage-
Derived Morphogenetic Protein-1 (hCDMP-1) variant
polypeptides. Morphogenetic proteins are able to induce the
proliferation and differentiation of progenitor cells into functional
bone, cartilage, tendon, or ligament tissue.
Patent information
U.S. Provisional Application No. 60/689,346 filed 09 Jun 2005
(HHS Reference No. E-196-2004/0-US-01); PCT Application filed
Inventors: Malcolm C. Moos et al. (FDA)
Type of business relationship sought
Licensees sought: Available for non-exclusive or exclusive
licensing
Licensing contact
Company details
National Institutes of Health (NIH)
The NIH supports and conducts basic, clinical, and translational medical research, and investigates the causes, treatments, and cures for both common and rare diseases.
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