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Composition, Methods and Products Comprising Human Papillomavirus for Detecting and Treating a Cancer (00-25)

University of Arkansas for Medical Sciences
Detecting and treating cancer in any stage of development.

Mechanism of action

screening method

Full description

Composition, Methods and Products Comprising Human Papillomavirus for Detecting and Treating a Cancer

Applications: Detecting and treating cancer in any stage of development.

This invention comprises methods for screening patients for cancer wherein the methods detect an HPV in a biopsy from a patient.  Also, disclosed are compositions and products for screening and for treating cancer in a patient, as well as methods of treating a patient afflicted with a cancer.

Claims of issued patent:

1. A method of screening a patient for breast cancer, the method comprising: a) assaying for the presence of human papillomavirus in a sample from a biopsy taken from a patient, wherein said assaying comprises amplifying human papillomavirus gene sequences by use of a pair of primers to produce an amplified product, and probing said amplified product for the presence of HPV 16 and a second human papillomavirus selected from the group consisting of HPV18, HPV31, HPV33, HPV35, HPV45, HPV58, wherein said pair of primers is SEQ ID NO: 1 and SEQ ID NO: 2, and wherein presence of HPV 16 and said second human papillomavirus is indicative of breast cancer in said patient.

2. The method of claim 1 wherein the patient is a human, wherein the cancer is in any stage of development.

3. The method of claim 1 wherein the biopsy is obtained by performing the technique of ductal lavage on a breast of a patient.

4. The method of claim 1 wherein said amplifying is achieved by use of polymerase chain reaction amplification.

 5. The method of claim 1 wherein said amplifying is achieved by use of reverse-transcription polymerase chain reaction amplification.

            U.S. Patent #6,884,605

            Available for Exclusive Licensing

00-25 Hermonat

Development status

Early Stage

Patent information

U.S. Patent #6,884,605

Type of business relationship sought

Developmental partner to commercialize this patented innovation

Patent number

6,884,605

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