Out-licensing

Method of ES Cell Isolation: Development of the use of Stem Cells as a Platform Technology

The invention describes a method to efficiently isolate embryonic stem (ES) cells from preimplantation mammalian embryos. Using a method whereby an embryo is implanted into a feeder layer of cells and cultured under special conditions, a high level of efficiency of primary culture establishment can be achieved without the use of mechanical separation techniques, which are currently employed to isolate pluripotent stem cells.

The efficient isolation of ES cells is of great importance in the development of the use of stem cells as a platform technology. The efficiency of this isolation method is believed to be sufficient to derive primary cultures from a single preimplantation embryo without the need for surgical isolation of the pluripotent component. Further, as this isolation method uses a defined culture medium, it makes this technique more attractive to researchers and commercial entities from a quality control and a regulatory point of view.

Conclusion

We have developed a novel method of ES cell isolation.

Relevance/Opportunity

A provisional patent application has been filed. We are looking to license this technology to partners interested in adopting this technique for their own research and development programs and/or collaboration for the further development and refinement of this technique.

Preclinical